Hodgkin’s Lymphoma Presenting with Myocardial Metastasis and Heart Failure

Authors

  • Maliheh Khoddami1 Associate Professor of Pathology, Shahid Beheshti University of Medical Sciences ,Tehran
  • Seyed Farzad Azarin Senior Resident of Pathology, Shahid Beheshti University of Medical Sciences ,Tehran
  • Zeinab Amirimoghaddam Assistant professor of Pediatrics, Shahid Beheshti University of Medical Sciences ,Tehran
Abstract:

Although involvement of the heart by malignant lymphoma is relatively common, it is unusual to be detected premortem. We report a case of Hodgkin's lymphoma who presented with systemic signs and symptoms including abdominal distension, weakness, pallor, chills and fever, hepatosplenomegaly and generalized lymphadenopathy as well as signs of heart failure. Echocardiography revealed lucent myocardial lesions, pericardial effusion, and left ventricular hypertrophy. Right cervical lymph node and bone marrow biopsies established the diagnosis of nodular sclerosis Hodgkin's lymphoma with bone marrow involvement. After 14 periods of chemotherapy, systemic and cardiac abnormalities improved. To the best of our knowledge, Hodgkin's lymphoma primarily presenting with myocardial metastasis and heart failure is not previously reported.  

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Journal title

volume 1  issue 4

pages  177- 180

publication date 2006-09-01

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